Abstract:As a main road running from south to north in the east of Tianhe District of Guanghou, Chepo Road North Extension Line can greatly improve the south-north traffic conditions in the east of Tianhe District after constructed so as to promote the area exchange and economic development. As the important control node of the project, there are the railways, urban expressways, main roads, secondary roads and different grades of road in the range of Guangyuan Interchange including the requirements of the multi-direction traffic transfer functions. It is necessary to comprehensively analyze various influencing factors during the scheme design. Many schemes are compared through the alignment technical standards of the main line, the main traffic functions of interchange, the influences on the current roads and environment, and the investment scales in order to achieve the best scheme. The design of Guangyuan Interchange Node can provide the certain reference for the design of the complicated urban interchanges.