Abstract:SIn recent years, with the rapid development of the national highway, large prefabricated box girder is widely used in highway construction. In the whole span box girder design, prefabrication and installation, the technology is also gradually mature, the span, bridge deck width, weight and structural form of the whole span box girder are constantly breaking new records. The whole-hole precast box girder brings great difficulty to the safety management because of the characteristics of single beam plate weight, complex technology, high equipment Operation Requirement and serious accident consequence, therefore, the safety management of large precast components is particularly important. Taking the Ningbo Phase I project of hangzhou-ningbo double line in Zhejiang Province as an example, this paper expounds the safety control during the prefabrication and installation of 50m1745t full-span box girder.