Abstract:The background project is the main bridge of pingcheng Street west extension in Datong city, Shanxi Province, which spans both railway marshalling yards and several important railway lines. This paper mainly introduces the structural design and calculation of the main line super large bridge, which adopts the bi-directional asymmetric single tower central cable plane cable-stayed bridge, the span layout is (41+50+163) m, the tower column and the main beam are steel concrete mixed structure, in order to reduce the influence on the railway, adopts the construction of rotating body. The results of static, local and dynamic calculation show that the structure design is reasonable and the construction is safe and reliable. It can provide reference for the design and construction of similar Bridges.