Abstract:SBased on 3×18.6m continuous box girder of a viaduct project which is Haikou Port as study background, and analysis under the specifications for seismic design of highway bridges[1](JTG T 2231-01-20), and the finite element software is used for seismic design analysis. The study shows that: (1) It is suitable for continuous beam bridges to adopt seismic mitigation and isolation design in liquefaction site in high-intensity area. (2) The seismic mitigation and isolation design is adopted, the basic period of the structure is long, the nonlinear characteristics are strong, and the time history method is more suitable for analysis. (3) After eliminating the liquefaction soil between piles, the stress of the bridge substructure, especially the pile foundation, under earthquake action is improved.