Open caisson is a common construction method for some pump well structures with the large buried depth because of its strong integrity, good structural stability and wide range of applicable soil. Taking the construction of open caisson in the influent pumping house project of a wastewater treatment plant (WWTP) in Suining City as an example, the whole construction process of this project is expounded in detail under the geological conditions of sand and pebbles, through the analysis of geological and hydrological characteristics. The construction scheme of combining that the open caisson is sunk by drainage and without drainage is selected to smoothly completed, which can be referred for the similar projects.