Aiming at the present situation of using many admixtures to improve the anti-ultraviolet aging ability of asphalt and asphalt mixture, the macro-performance index, micro-performance index and cost factor of compound modified asphalt are comprehensively considered. The entropy weight-TOPSIS theory is used to optimize 6 different inhibitor schemes. The result shows that two compound modified asphalt schemes determined by this theory have the good cost performances, and can satisfy the requirements of anti-ultraviolet characteristics of asphalt pavement, which provides the new technical approach for the design and optimization of modified asphalt formulation in the future.