Abstract:The new project of Pudan Expressway (Pujiang Ring Road of S401 Line) is a typical mountain highway project, which is characterized by the large ground elevation difference, high mountains and deep ditches, and frequent changes. The design overview of the project and the design essentials of the bridge are mainly introduced. The application of prefabricated bridge structure, optimization design of control node engineering, design of Beijing-Kunming Expressway (Chengya Section) Crossover Project, design of bridge structure spanning the section of Pujiang River, design of bridge structure anti-seismic measures and protection design of abutment steep slope section are mainly discussed.