Abstract:All the regions in China are in the active zone of plate and shell. In recent years, due to the intensification of plate and shell activities, the regions have suffered many different degrees of earthquake disasters, which has brought great loss of life and property to the people. Under the action of earthquake, if the main pylon as the main load-bearing component of cable-stayed bridge is damaged, the overall damage risk of cable-stayed bridge will be significantly increased. Taking a cable-stayed bridge as an engineering example, through SAP2000 finite element analysis software, based on the performance seismic design theory subject knowledge, by using the IDA time-procedure analysis result and according to the capacity demand ratio model method, the seismic vulnerability curve of each key section of the main pylon of the cable-stayed bridge is drawn, and then the seismic vulnerability analysis on the main pylon of cable-stayed bridge is carried out. The results show that under the action of longitudinal earthquake, the bottom section of the middle pylon of the main pylon is a vulnerable section.