Baietan Avenue is the only urban north-south sub-arterial road in the area near the river of Baietan Business District in Guangzhou. Baietan Avenue spanning the current open section of the Pearl River Tunnel is one of the key nodes to connect the whole line. The spatial relationship between Baietan Avenue and the current Pearl River Tunnel and subway structure is comprehensively considered. Under the condition of meeting the protection requirements of the existing subway and not affecting the structure and operation safety of the Pearl River Tunnel, the overall design scheme of reconstructing the side wall of the open section of the current tunnel to add the abutment capping as a new bridge abutment and spanning the open section of the existing tunnel is proposed. The relevant design research ideas can provide the reference for similar projects.